Accessories for VWR® Vortex Mixers
Supplier: VWR International
Shaker, Vortex Mixer, VWR®, Ampule holder, 15 to 17 mm
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VWR® Wire Frame Shelves
Supplier: VWR International
Extra wire frame shelves that fit the VWR® 14, 17, and 20 cu. ft. refrigerators.
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Avantor® Hichrom HI-17, GC Columns
Supplier: VWR International
General purpose polar phase for a wide range of applications, ideal as confirmation analysis column. Ideal in a GCxGC configuration as polar dimension column. HI-17 is a Crossbonded phase and assure a long lifetime even under high temperature limits.
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Mouse Recombinant IL-17F (from E. coli)
Supplier: VWR International
Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-β1).
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VWR® Cleanroom Tab Dividers
Supplier: VWR International
11×17" cleanroom binder tab dividers.
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Human Recombinant IL-17F (from E. coli)
Supplier: VWR International
Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-b1).
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Masterflex® Solenoid-Operated Pinch Valve For Masterflex® Pump Tubing, Avantor®
Supplier: VWR International
Specifically designed for Masterflex® pump tubing.
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VWR® Culture Tubes, Plastic, with Dual-Position Caps
Supplier: VWR International
Choose from clear polystyrene or natural polypropylene disposable tubes.
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Human Recombinant TH17 CELL POLARIZING PB (from E. coli)
Supplier: VWR International
Cytokines for polarizing human T cells into Th17 cells. T helper 17 cells (Th17) are a distinct type of T cell subset that are thought to be important in immunity against microbes at the epitilial and mucosal interfaces of the body. Disruption of the regular function or balance of Th17 cells is thought to be involved in several autoimmune diseases and/or opportunistic infections. Th17 cells are characterized by their ability to produce IL-17, IL-22 and IL-21. Th17 cells can be cultured from naive CD4+ T cells by culturing them in the presence of anti-CD3 and anti-CD28 stimulation with recombinant IL-6 and recombinant TGF-β 1.
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Avantor® Hichrom HI-17 MS, GC Columns
Supplier: VWR International
Really versatile general purpose polar phase for a wide range of applications. Ideal in confirmation analysis. HI-17 MS is an MS grade low-bleeding crossbonded column and assure a long lifetime even under high temperature limits.
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Human Recombinant G-CSF (from E. coli)
Supplier: VWR International
Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNF-α), interleukin 1 (IL-1), or interleukin 17 (IL-17).
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Human Recombinant G-CSF (from E. coli)
Supplier: VWR International
Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNF-α), interleukin 1 (IL-1), or interleukin 17 (IL-17).
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Human Recombinant IL-17AF (from E. coli)
Supplier: VWR International
Interleukin 17AF (IL-17AF) is a heterodimer that is composed of the interleukin 17A (IL-17A) and interleukin 17F (IL-17F) members of the IL-17 family of cytokines. IL-17AF is produced by T helper 17 cells (Th17) following interleukin 23 (IL-23) stimulation. IL-17AF signals through the IL-17RA/IL-17RC receptor complex and functions to regulate inflammatory responses.
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Accessories for Horizon Horizontal Centrifuges, 755 Series, Drucker Diagnostics
Supplier: VWR International
This is a 17 x 125mm tube holder can be used with the Model 614B, 614V, 755-12, and 755V-12
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Rat Recombinant IL-17F (from E. coli)
Supplier: VWR International
Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-β1).
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VWR® Berzelius Tall Form Beakers
Supplier: VWR International
Our new high-quality borosilicate Berzelius beakers meet ASTM standard and are a great value.
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VWR® Slide Tray Clasps
Supplier: VWR International
Color clasps are ideal for color coding identification and to keep slide folders securely closed.
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Mouse Recombinant IL-17F (from E. coli)
Supplier: VWR International
Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-β1).
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Human Recombinant IL-17F (from E. coli)
Supplier: VWR International
Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating factor (GM-CSF) cytokines. IL-17F also functions to regulate matrix turnover rates, inhibit endothelial cell angiogenesis, and induce the endothelial cell expression of interleukin 2 (IL-2), monocyte chemoattractant protein-1 (MCP-1), and transforming growth factor beta 1 (TGF-b1).
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VWR® Tri-Pour® Graduated Disposable Beakers, Polypropylene
Supplier: VWR International
Transparent polypropylene beaker with three pouring lips for dripless dispensing.
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Masterflex® L/S® Pump Tubing, Gore® STA-PURE® PFL-Series, Avantor®
Supplier: VWR International
High-performance pump tubing for challenging applications.
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Mouse Recombinant G-CSF (from E. coli)
Supplier: VWR International
Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte proliferation, terminal differentiation, and activation. G-CSF synthesis occurs in monocyte, macrophage, epithelial, endothelial, and fibroblast cells after activation by bacterial endotoxins, tumor necrosis factor alpha (TNF-α), interleukin 1 (IL-1), or interleukin 17 (IL-17). The functional activity of G-CSF is mediated through the granulocyte colony-stimulating factor receptor (G-CSF-R) to activate JAK/STAT and MAPK signal transduction pathways. G-CSF also promotes neurogenesis and inhibits neuronal apoptosis. Human and mouse G-CSF proteins are cross-reactive.
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17-AAG
Supplier: RPI
17-AAG (17-Allylamino-17-demethoxygeldanamycin) is a synthetic derivative of geldanamycin. Like geldanamycin, 17-AAG is recognised for its role as an inhibitor of heat shock protein 90 (Hsp90), a molecular chaperone involved in protein folding and stabilisation.
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17-AAG (synthetic)
Supplier: Novus Biologicals
Glendanamycin (GA), a benzoquinone ansamycin antibiotic, interferes with the action of Hsp90 leading to degradation of Hsp90 client proteins. GA itself however has undesirable properties such as poor aqueous solubility and liver toxicity; therefore, numerous analogs have been synthesized, such as 17-AAG. 17-AAG is an HSP-90 inhibitor that displays a 100-fold higher affinity for HSP-90 derived from tumor cells compared to HSP-90 from normal cells. 17-AAG inhibits Akt activation and expression in tumors and synergizes with a number of antitumor agents such as taxol, cisplatin and UCN-01 (400 nM 17-AAG, U937 cells).
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Masterflex® L/S® Precision Pump Tubing, C-Flex® ULTRA, Avantor®
Supplier: VWR International
Longest life of any C-Flex® formulation.
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Masterflex® Union Fittings, Hose Barb, Y-Connector, Nylon, Avantor®
Supplier: VWR International
No tools needed for assembly.
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Mouse Recombinant IL-17AF (from E. coli)
Supplier: VWR International
Interleukin 17AF (IL-17AF) is a heterodimer that is composed of the interleukin 17A (IL-17A) and interleukin 17F (IL-17F) members of the IL-17 family of cytokines. IL-17AF is produced by T helper 17 cells (Th17) following interleukin 23 (IL-23) stimulation. IL-17AF signals through the IL-17RA/IL-17RC receptor complex and functions to regulate inflammatory responses. IL-17AF induces chemokine and airway neutrophilia production, similar in function to IL-17A and IL-17F homodimers. In regard to these functions, IL-17AF is less active than the IL-17A homodimer and shows greater activity than the IL-17F homodimer. Human and rat IL-17AF are active on mouse cells.
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17-AAG 99%
Supplier: Thermo Scientific Chemicals
17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2