Pierce™ EZ-Link® Sulfhydryl Reactive Biotinylation Reagents, Thermo Scientific

: Invitrogen

: Invitrogen

Sulfhydryl groups are the second most common target for modification in biological studies. They are found as exposed cysteines in protein and peptides. Sulfhydryl group biotinylation provides an advantage in some applications; for example, targeting a sulfhydryl group can help preserve the biological activity of an enzyme when amines are found at the active site.

Maleimide-PEG₂ and PEG₁₁-Biotin: Water-soluble

Biotin-BMCC: Reacts with sulfhydryl (-SH) groups at 6.5 to 7.5 pH. Avoids potential modification of tyrosine residues that can be associated with Iodoacetyl-Biotin. Must be dissolved in DMSO or DMF before use.

Iodoacetyl-PEG₂-Biotin: Water soluble. Reacts with sulfhydryl (-SH) groups at basic to neutral pH. Coupling reactions occur in the dark.

Iodoacetyl-LC-Biotin: Reacts with sulfhydryl (-SH) groups at basic to neutral pH. Coupling reactions occur in the dark. Must be dissolved in DMSO or DMF before use.

Reacts with sulfhydryl (-SH) groups at acidic to neutral pH. PEG₁₁-Biotin has an extra long spacer arm that reduces steric hindrance.

Product Information

Catalog #
Supplier #
Spacer arm
Molecular weight
Size
Supplier no.
Availability
Price
EZ-Link™ Iodoacetyl-LC-Biotin
EZ-Link™ Iodoacetyl-LC-Biotin
PI21333
Certificates SDS
21333
27.1 Å
510.43 g/mol
50 mg
21333
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Each (50mg)
Each (50mg) - $499.91
$499.91
Each (50mg)
$499.91
Minimum order quantity is 1
Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
EZ-Link™ Iodoacetyl-PEG₂-Biotin
EZ-Link™ Iodoacetyl-PEG₂-Biotin
PI21334
Certificates
21334
24.7 Å
542.43 g/mol
50 mg
21334
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Each
Each - $316.62
$316.62
Each
$316.62
Minimum order quantity is 1
Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
EZ-Link™ Biotin-HPDP
EZ-Link™ Biotin-HPDP
PI21341
Certificates SDS
21341
29.2 Å
539.78 g/mol
50 mg
21341
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Each
Each - $416.00
$416.00
Each
$416.00
Minimum order quantity is 1
Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
EZ-Link™ Biotin-BMCC
EZ-Link™ Biotin-BMCC
PI21900
Certificates SDS
21900
32.6 Å
533.68 g/mol
50 mg
21900
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Each (50mg)
Each (50mg) - $394.48
$394.48
Each (50mg)
$394.48
Minimum order quantity is 1
Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
EZ-Link™ Maleimide-PEG₂-Biotin
EZ-Link™ Maleimide-PEG₂-Biotin
PI21901
Certificates
21901BID
29.1 Å
525.62 g/mol
50 mg
21901
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Each
Each - $392.11
$392.11
Each
$392.11
Minimum order quantity is 1
Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
EZ-Link™ Maleimide-PEG₁₁-Biotin
EZ-Link™ Maleimide-PEG₁₁-Biotin
PI21911
Certificates SDS
21911
59.1 Å
922.09 g/mol
25 mg
21911
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Each (25mg)
Each (25mg) - $517.68
$517.68
Each (25mg)
$517.68
Minimum order quantity is 1
Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.