Pertussis toxin (PT), a virulence factor produced by Bordetella pertussis, is a multi-subunit toxin which binds to most cultured mammalian cells and targets specific G protein, inhibiting the ability of the G protein to function in signaling pathways
Depending on the function of the G protein, the effects of PT can vary. This ability to inhibit pathways utilizing the Gi family of protein-coupled receptors is the basis of the use of PT as a tool in cell biology. PT plays a role in infection by suppressing and modulating various host immune responses to Bordetella pertussis. PT has been used to stimulate experimental autoimmune diseases in rodent models, such as experimental auto immune encephalitis (EAE).
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- SizeSupplier no.
- Pertussis Toxin Islet-Activating Protein Lyophilized in bufferPertussis Toxin Islet-Activating Protein Lyophilized in buffer18050 µg180Each (50µG)$615.38
- Pertussis Toxin Islet Activating Protein (in glycerol), Ships on blue ice overnightPertussis Toxin Islet Activating Protein (in glycerol), Ships on blue ice overnight179A50 µg179AEach (50µG)$621.54
- FIMBRIAE 2/3 from Bordetella PertussisFIMBRIAE 2/3 from Bordetella Pertussis102946-46018650 µg186Each (50µG)$1,341.54
- Pertussis Toxin Islet Activating Protein Lyophilized (Salt-Free)Pertussis Toxin Islet Activating Protein Lyophilized (Salt-Free)18150 µg181Each (50µG)$627.69