- Antibody Type:Primary
- Antigen Name:apoptotic chromatin condensation inducer 1
- Antigen Symbol:ACIN1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western Blot:Yes
- Size:0.1 mg
- Form:Liquid
- Gene ID:Q9UKV3
- Antigen Synonyms:ACIN1
- Storage Buffer:Acinus Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular Weight:220 kDa
- Storage Temperature:Acinus antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Shipping Temperature:4 °C
- Immunogen:Acinus antibody was raised against a 35 amino acid peptide near the center of human Acinus. The immunogen is located within amino acids 760 - 810 of Acinus.
- Tested Applications:Immunocytochemistry
- Purification:Acinus Antibody is affinity chromatography purified via peptide column.
- Cat. No.:89415-372
- Supplier no.:2219
Acinus Antibody: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS'.
Type: Primary
Antigen: ACIN1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human