T4 RNA Ligase 2, New England BiolabsSupplier: New England Biolabs
M0239L M0239L M0239S M0239S
101386-086EA 353.62 USDCA101386-086 101386-086 CA101386-088 101386-088
T4 RNA Ligase 2, New England Biolabs
Nucleic Acid Reagents Cloning Kits and Ligation
T4 RNA Ligase 2, also known as T4 Rnl2 (gp24.1), has both intermolecular and intramolecular RNA strand joining activity
Unlike T4 RNA Ligase 1, T4 RNA Ligase 2 is much more active joining nicks on double stranded RNA than on joining the ends of single stranded RNA. The enzyme requires an adjacent 5´ phosphate and 3´ OH for ligation. The enzyme can also ligate the 3´ OH of RNA to the 5´ phosphate of DNA in a double stranded structure.