Tenovin-1
Supplier: MilliporeSigma
PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable benzoylthiourea compound that activates p53 and displays antitumor properties. Acts as a reversible and noncompetitive inhibitor of sirtuins1,2 (IC50 ~ 10 ¦M for SIRT2) with selectivity over HDACs. Shown to protect p53 from MDM2-mediated degradation, induce cell death, and delay tumor growth in several cell lines and in xenograft mouse model (92 mg/kg, i.p.). Purity: ?98% by HPLC. Ref.: Lain, S., et al. 2008. Cancer Cell 13, 454.
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Tenovin-1 98%
Supplier: Ambeed
N-((4-Acetamidophenyl)carbamothioyl)-4-(tert-butyl)benzamide, Purity: 98%, CAS Number: 380315-80-0, Appearance: White to off-white solid, Storage: Sealed in dry, Room Temperature, Size: 1mg